EFFICACY COMPARISON OF ACITRETIN VERSUS NARROW BAND ULTRAVIOLET B IN THE TREATMENT OF PSORIASIS

Abstract

To compare the efficacy of Acitretin versus Narrow Band Ultraviolet B in the treatment of chronic Psoriasis This randomized clinical trial was carried out at the department of dermatology DHQ Sargodha Hospital from Dec 2021 to Dec 2022. After getting approval from the Ethical review committee, 80 psoriasis patients were selected. They were suffering from moderate to severe plaque psoriasis. They were divided into two groups of 40 each. Group A patients received acitretin while Group B patients received Narrow Band Ultraviolet B for 6 weeks. Efficacy end point was decided to be PASI 50. In group A, 82%patients achieved PASI 50 while in Group B 39% patients achieved PASI 50 . The efficacy of acitretin was significantly higher than that of Narrow Band Ultraviolet B: Acitretin is a useful treatment modality for the treatment  of moderate & severe plaque psoriasis.